(αR,βS)-β-(Benzoylamino)-α-hydroxybenzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-12-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 2-Debenzoyl-2-tigloylpaclitaxel; Isocephalomannine; Paclitaxel impurity A, Paclitaxel EP Impurities; Paclitaxel - impurity A
杂质:
Paclitaxel impurity A; Paclitaxel - impurity A
CAS号:
173101-54-7
分子式:
C₄₅H₅₃NO₁₄
外观:
白色至白色固体
熔点:
>150°C (dec.)
分子量:
831.9
储存:
-20˚C Freezer, Under Inert Atmosphere
溶解度:
Chloroform (Slightly), Methanol (Slightly)
种类:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Iso Cephalomannine is a Cephalomannine (C258500) isomer as an impurity in Paclitaxel (P132500) active pharmaceutical ingredient. Paclitaxel impurity A. It binds to the N-terminal 31 amino acids of the beta-tubulin subunit in the microtubule, rather than to tubulin dimers. Paclitaxel - impurity A.
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