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产品基本信息
产品编号:A794712
产品名称:Avosentan-d3
产品CAS:1206674-82-9
规格含量:10mg
产品价格:面议
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产品详细介绍
标准品编号:
A794712
名称:
Avosentan-d3
别名:
N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide-d3; Ro 67-0565-d3; SPP 301-d3;
CAS号:
1206674-82-9
备用CAS:
未标记: 290815-26-8
分子式:
C₂₃H₁₈D₃N₅O₅S
分子量:
482.53
类别:
Building Blocks; Isotopic Labeled Analogues;
应用:
Labelled Avosentan, a competitive antagonist of Endothelin-1 (ET-1) with a high selectivity for the ETA receptor. Avosentan may be a potential option in the treatment of glaucoma.
文献
Dieterle, W. et al.: J. Clin. Pharmacol., 44, 59 (2004); Dieterle, W. et al.: Int. J. Clin. Pharmacol. Ther., 43, 178 (2005); Wang, R.-F. et al.: Curr. Eye Res., 36, 41 (2011);