BAY-X 1005_128253-31-6_B127620_【莱耀标准品网】

产品基本信息

产品编号：B127620

产品名称：BAY-X 1005

产品CAS：128253-31-6

规格含量：2.5mg

产品价格：面议

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产品详细介绍

标准品编号:	B127620
名称:	BAY-X 1005
别名:	(R)-Î±-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic Acid; Veliflapon
CAS号:	128253-31-6
分子式:	C₂₃H₂₃NO₃
分子量:	361.43
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	Bay-X-1005 is a potent inhibitor of 5-lipoxygenase activating protein (FLAP). It inhibits the production of leukotriene B4 in A23187-stimulated leukocytesd LTB4 with an IC50 value of 220 nM, and blocks IgE mediated airway contractions. It has also anti-inflammatory activity.
文献	Peddinghaus, M. et al: J.Pharmacol.Exp.Ther. 267 51 (1993); Hatzelmann et al.: Agents Actions 43 64 (1994);

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