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产品基本信息
产品编号：E945420
产品名称：Everolimus Retroaldol Degradation Product
产品CAS：1708118-13-1
规格含量：10mg
产品价格：面议
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产品详细介绍
标准品编号:
E945420
名称:
Everolimus Retroaldol Degradation Product
别名:
(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate; Everolimus Ring-opening Impurity
杂质:
Everolimus Impurity
CAS号:
1708118-13-1
分子式:
C₅₃H₈₃NO₁₄
外观:
白色至白色固体
熔点:
45-50°C
分子量:
958.22
储存:
Amber Vial, -86°C Freezer, Under inert atmosphere
溶解度:
Chloroform (Slightly), Methanol (Slightly)
稳定性:
Light and temperature Sensitive
种类:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Everolimus Retroaldol Degradation Product is an impurity of Everolimus (E945400). Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Everolimus Impurity D
参考文献
Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),
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