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产品基本信息
产品编号：L175808
产品名称：Lapatinib
产品CAS：231277-92-2
规格含量：250mg
产品价格：面议
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产品详细介绍
标准品编号:
L175808
名称:
Lapatinib
别名:
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine; 4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline; GSK 572016; GW 2016; GW 572016; GW 572016X; N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-[[[2-(methanesulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine; N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine; N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine; N-[4-(3-Fluorobenzyloxy)-3-chlorophenyl]-6-[5-[[2-(methylsulfonyl)ethylamino]methyl]furan-2-yl]quinazolin-4-amine; Tycerb; Tykerb; Tyverb;
CAS号:
231277-92-2
分子式:
C₂₉H₂₆ClFN₄O₄S
外观:
淡黄色固体
熔点:
144-146ºC
分子量:
581.06
储存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly, Sonicated)
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Lapatinib is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. This drug is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.
参考文献
Konecny, G., et al.: Cancer Res., 66, 1630 (2006); Geyer, C., et al.: N. Engl. J. Med., 355, 2733 (2006);
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