(2S)-[(2S)-[(2R)-Amino-3-mercapto]-propylamino-(3S)-methyl]pentyloxy-3-phenylpropionyl-methionine Sulfone Isopropyl Ester Bis Hydrchloride;
CAS号:
1177806-11-9
参考CAS号:
freebase: 1178093-87-2
分子式:
C₂₆H₄₇Cl₂N₃O₆S₂
外观:
白色固体
熔点:
160-165°C
分子量:
632.7
储存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly)
种类:
Standards; Enzyme Activators and Inhibitors;
应用:
Ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expressoin and arrests cells at G1. Causes enhanced mitotic sensitivity to taxol.
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