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β-Nicotinamide Mononucleotide
产品基本信息
产品编号:N407765
产品名称:β-Nicotinamide Mononucleotide
产品CAS:1094-61-7
规格含量:25mg
产品价格:面议
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产品详细介绍
标准品编号: N407765
名称: β-Nicotinamide Mononucleotide
别名: 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt; 3-Carbamoyl-1-β-D-ribofuranosylpyridinium Hydroxide, 5'-Phosphate Inner Salt; NMN; Nicotinamide Mononucleotide; Nicotinamide Ribonucleoside 5'-Phosphate; Nicotinamide Ribonucleotide; Nicotinamide Ribotide; β-D-NMN; β-NMN;
CAS号: 1094-61-7
分子式: C₁₁H₁₅N₂O₈P
外观: 白色至Yellow Solid
熔点: >96°C (dec.)
分子量: 334.22
储存: Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
溶解度: Methanol (Slightly), Water (Slightly)
稳定性: Very Hygroscopic
种类: Standards; Pharmaceutical/API Drug Impurities/Metabolites; Nicotine Derivatives and Metabolites;
应用: A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
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