3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthylium Chloride; 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic Acid Methyl Ester Monohydrochloride; R 22420; R 302; RH 123;
CAS号:
62669-70-9
参考CAS号:
104114-27-4--free base
分子式:
C₂₁H₁₇ClN₂O₃
外观:
Red Solid
分子量:
380.83
储存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Water (Slightly)
类别:
Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).