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产品基本信息
产品编号：V094325
产品名称：L-Valine Methyl Ester Hydrochloride
产品CAS：6306-52-1
规格含量：25g
产品价格：面议
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产品详细介绍
标准品编号:
V094325
名称:
L-Valine Methyl Ester Hydrochloride
别名:
(S)-Valine Methyl Ester Hydrochloride; Methyl (S)-2-Amino-3-methylbutanoate Hydrochloride; Methyl (S)-Valinate Hydrochloride; Methyl L-Valinate Hydrochloride; Methyl Valinate Hydrochloride; NSC 197198; NSC 22920; Valine Methyl Ester Hydrochloride
CAS号:
6306-52-1
参考CAS号:
Free Base: 4070-48-8
分子式:
C₆H₁₄ClNO₂
外观:
白色固体
熔点:
163-165°C
分子量:
167.63
储存:
冰箱
溶解度:
DMSO, Methanol
类别:
Building Blocks; Chiral Molecules;
应用:
L-Valine Methyl Ester Hydrochloride is used in the synthesis of Valaciclovir (V085000), the L-Valine ester prodrug of Acyclovir (A192400), orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.
参考文献
McClean, K. et al.: Tetrahedron Lett., 52, 215 (2011); Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992), Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),
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