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产品基本信息
产品编号：A632980
产品名称：3-Aminopiperidine-2,6-dione Hydrochloride
产品CAS：24666-56-6
规格含量：5g
产品价格：面议
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产品详细介绍
标准品编号:
A632980
名称:
3-Aminopiperidine-2,6-dione Hydrochloride
别名:
3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Amino-2,6-piperidinedione Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride;ÂDL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride
CAS号:
24666-56-6
备用CAS:
Free Base: 2353-44-8
分子式:
C₅H₉ClN₂O₂
外观:
白色固体
熔点:
>208ºC (dec.)
分子量:
164.59
储存:
冰箱保存
溶解度:
DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated)
类别:
Building Blocks; Miscellaneous;
应用:
3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induceÂubiquitination and degradation of CK1α in del(5q) MDS.ÂIt can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.
文献
Kronke, J., et al.: Nature 523, 183 (2015);ÂLiu C., et al.:ÂFaming Zhuanli Shenqing CNÂ105348257ÂAÂ20160224 (2016);ÂRao, R., et al. :ÂPCT Int. Appl. WOÂ2016024286ÂA2Â20160218 (2016)
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