产品基本信息
产品编号：T295980
产品名称：2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
产品CAS：230615-51-7
规格含量：250mg
产品价格：面议
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产品详细介绍
标准品编号:
T295980
名称:
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
别名:
1-(4,5-Dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)ethanone
CAS号:
230615-51-7
分子式:
C₁₃H₁₂F₃NO
分子量:
255.24
类别:
Building Blocks;
应用:
2,3,4,5-tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine is a reactant used in the preparation of Varenicline, a nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation.
参考文献
Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988); Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003); Tapper, A., et al.: Science, 306, 1029 (2004); Coe, J., et al.: J. Med. Chem., 48, 3474 (2005); Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006)
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