(2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-[2-(Aminooxy)-2-oxoethyl]-6-methoxy-2,5,17-trimethyl-1,22-diazanyl Ester 2,4,8,10,14,18,20-Docosaheptaenedioic Acid Triammonium Salt
参考CAS:
Free Base: 1177154-51-6
分子式:
C₂₈H₃₈O₇ • 3NH ₃
分子量:
486.6031703
类别:
Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors;
应用:
Bongkrekic Acid is a natural toxin first isolated from coconut tempeh contaminated with bacteria. It is a polyunsaturated long-chain fatty acid derivative that acts as a potent inhibitor of the mitochondrial adenine nucleotide (ADP/ATP) translocase (Ki < 2 nM). Despite its high affinity, bongkrekic acid has a slow rate of action in intact preparations, as it must permeate the inner mitochondrial membrane to bind the translocase.
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