4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)pic__A609735

产品基本信息

产品编号：A609735

产品名称：4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)pic

产品CAS：

规格含量：50mg

产品价格：面议

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产品详细介绍

标准品编号:	A609735
名称:	4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide Hydrochloride
分子式:	C₂₅H₂₀ClF₂N₅O₄
分子量:	527.91
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide Hydrochloride is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
参考:	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)

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