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GSK PERK Inhibitor
产品基本信息
产品编号:G797800
产品名称:GSK PERK Inhibitor
产品CAS:1337531-89-1
规格含量:2mg
产品价格:面议
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产品详细介绍
标准品编号: G797800
名称: GSK PERK Inhibitor
别名: 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone; 3-Fluoro-GSK2606414
CAS号: 1337531-89-1
分子式: C₂₄H₁₉F₄N₅O
外观: 白色至淡黄色固体
熔点: 233-238°C (dec.)
分子量: 469.43
储存: 冰箱
溶解度: DMSO (Slightly), Methanol (Slightly, Heated)
种类: Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: GSK PERK Inhibitor is an inhibitor of PERK, an important transmembrane protein of endoplasmic reticulum (ER). GSK PERK Inhibitor can be useful in the treatment of cancer, ocular diseases, and diseases associated with activated unfolded protein response pathways. As a result, GSK PERK Inhibitor has potential use in the treatment of diseases such as Alzheimer's disease, stroke, Type 1 diabetes, Parkinson disease, Huntington's disease, amyotrophic lateral sclerosis, myocardial infarction, cardiovascular disease, atherosclerosis, and arrhythmias, and more specifically cancers of the breast, colon, pancreatic, and lung.
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