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Myriocin
产品基本信息
产品编号:M884400
产品名称:Myriocin
产品CAS:35891-70-4
规格含量:2mg
产品价格:面议
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产品详细介绍
标准品编号: M884400
名称: Myriocin
别名: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; [2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; (+)-Myriocin; ISP-I; NSC 177379; Thermozymocidin; (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid;
CAS号: 35891-70-4
分子式: C₂₁H₃₉NO₆
外观: 白色至白色固体
熔点: >175°C (dec.)
分子量: 401.54
储存: Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度: DMSO (Sparingly), Methanol
种类: Standards; Chiral Molecules; Amino Acids; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
应用: Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine palmitoyltransferase and thus blocks the synthesis ceramide, a precursor in sphingomyelin and glycosphingolipid biosynthesis. As a result Myriocin is a useful biochemical research tool for depleting cells of sphingolipids.
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