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产品基本信息
产品编号：O870040
产品名称：1-Oxo Fexofenadine Methyl Ester
产品CAS：154477-55-1
规格含量：10g
产品价格：面议
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产品详细介绍
标准品编号:
O870040
名称:
1-Oxo Fexofenadine Methyl Ester
别名:
4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic Acid Methyl Ester; 2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic Acid Methyl Ester; Methyl 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylphenylacetate;
CAS号:
154477-55-1
分子式:
C₃₃H₃₉NO₄
外观:
白色至白色固体
熔点:
110-113°C
分子量:
513.67
储存:
Room Temp
溶解度:
DMSO (Slightly), Methanol (Slightly)
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
1-Oxo Fexofenadine Methyl Ester, is an intermediate in the preparation of Fexofenadine (F322470). It can also be used for the synthesis of an oxidation metabolite of Terfenadine (T114500),a H1-receptor antagonist.
参考文献
Garteiz, D.A., et al.: Arzneim.-Forsch., 32, 1185 (1982), Rampe, D., et al.: Mol. Pharmacol., 44, 1240 (1993), Obradovic, T., et al.: Pharm. Res., 24, 318 (2007); Kawai, S., et al.: J. Org. Chem., 59, 2620 (1994);
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