Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-(Aminocarbonyl)-3-hydroxy-α-methyl-L-tyrosine is an intermediate used in the synthesis of (S)-(-)-Carbidopa (C178985), which is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.