Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-Nitroso-N-methylbenzylamine induced neoplasia in mice. Mice treated intragastrically with N-Nitroso-N-methylbenzylamine developed multiple tumours. Mice carrying one inactivated Fhit allele (Fhit +/- mice) are highly susceptible to tumor induction by N-nitrosomethylbenzylamine