N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide Mesylate; N-Desmethyl Gleevec Mesylate; CGP-74588 ; Norimatinib; STI 509-00;
CAS号:
404844-03-7
参考CAS号:
Free Base: 404844-02-3
分子式:
C₂₉H₃₃N₇O₄S
外观:
Light Yellow to Yellow Solid
熔点:
140-150°C
分子量:
575.68
储存:
冰箱保存
溶解性:
DMSO (Slightly), Methanol (Slightly)
种类:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-Desmethyl Imatinib Mesylate is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
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