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产品基本信息
产品编号：N200705
产品名称：(S)-(-)-Nadifloxacin
产品CAS：154357-42-3
规格含量：10mg
产品价格：面议
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产品详细介绍
标准品编号:
N200705
名称:
(S)-(-)-Nadifloxacin
别名:
(S)-9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic Acid; (5S)-9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid; (S)-9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-Benzo[ij]quinolizine-2-carboxylic Acid; Levonadifloxacin;
CAS号:
154357-42-3
分子式:
C₁₉H₂₁FN₂O₄
分子量:
360.38
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
应用:
(S)-(-)-Nadifloxacin is an anti-bacterial agent against multidrug-resistant Staphylococcus aureus. Also, it is derived from 6-Fluoro-2-methylquinoline (F595900), which is an quinoline derivative, a highly potent thrombin receptor antagonist.
参考文献
Hashimoto, K., et al.: Chem. Pharm. Bull., 44, 642-645 (1996); De Souza, N. J., et al.: J. Med. Chem., 48, 5232-5242 (2005); Davie, E., et al.: Biochemistry, 30, 10363 (1991), Vu, T., et al.: Nature, 353, 674 (1991), Nanevicz, T., et al.: J. Biol. Chem., 270, 21619 (1995), Grand, R., et al.: J. Biochem., 313, 353 (1996), Ahn, H., et al.: Mol. Pharmacol., 51, 350 (1997);
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