Amitriptyline N-β-D-Glucuronide-d6 is an isotope analog of Amitriptyline N-β-D-Glucuronide (A633360). Amitriptyline N-β-D-Glucuronide is used in biological studies for biphasic kinetics of quaternary ammonium glucuronide formation from amitriptyline and diphenhydramine in human liver microsomes. Also, this compound is used in analytical studies to detect amitriptyline and diphenhydramine N-glucuronides in human urine using HPLC with and without hydrolysis.