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Adaptaquin
产品基本信息
产品编号:A225100
产品名称:Adaptaquin
产品CAS:385786-48-1
规格含量:50mg
产品价格:面议
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产品详细介绍
标准品编号: A225100
名称: Adaptaquin
别名: 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol
CAS号: 385786-48-1
分子式: C₂₁H₁₆ClN₃O₂
分子量: 377.82
类别: Research Tools; Standards; Molecular Biology; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
应用: General Uses: Ischemic injury Research, Renal anemia, HIF Prolyl Hydroxylase Inhibitor, Antioxidant, Neuroprotective Description: Adaptaquin inhibits the HIF PHDs in brain in a dose dependent fashion and penetrates blood brain barrier (BBB). Exhibited functional recovery in intra-cerebral hemorrhage rat model; inhibits ATF4 gene. Potent HIF PHD inhibitor (hypoxia inducible factor), Selective PDH2 inhibitor. This compound is suitable for pyruvate dehydrogenase (PDH) related research.
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