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产品基本信息
产品编号：A628898
产品名称：[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester
产品CAS：379270-35-6
规格含量：1g
产品价格：面议
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产品详细介绍
标准品编号:
A628898
名称:
[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester
别名:
Phenyl Hydrogen [(R)-1-(6-Amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate;
CAS号:
379270-35-6
分子式:
C₁₅H₁₈N₅O₄P
状态：
白色固体
熔点：
237-239°C
分子量:
363.31
储存：
-20°C Freezer, Under inert atmosphere
溶解性:
Aqueous Acid (Slightly), DMSO (Heated, Sonicated)
类别:
Standards; Anti-virals/Anti-retrovirals;
应用:
[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
参考:
Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);
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