您的位置:对照品 > 标准品 > 欧洲药典标准品 >
产品基本信息
产品编号:H998000
产品名称:Hymenialdisine Methanoate
产品CAS:
规格含量:2mg
产品价格:面议
联系我们:
产品详细介绍
标准品编号:
H998000
名称:
Hymenialdisine Methanoate
别名:
(4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one Methanoate; (Z)-Hymenialdisine Methanoate;
参考CAS号:
free base: 82005-12-7; monomethonate 84094-94-0
分子式:
C₁₁H₁₀BrN₅O₂ • x(CH ₄O)
外观:
Pale Yellow to 淡黄色固体
熔点:
>245°C (dec.)
分子量:
324.133204
储存:
-20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Very Slightly)
种类:
Standards; Enzyme Activators and Inhibitors;
应用:
A potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. A marine sponge alkaloid, a natural product.
参考文献
Cheetham, G., et al.: J. Biol. Chem., 277, 42419 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Sharma, V., et al.: Bioorg. Med. Chem. Lett., 14, 4319 (2004), Anamika, et al.: Proteins, 58, 180 (2005), Birault, V., et al.: Curr. Med. Chem., 13, 1735 (2006),