(2S)-2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic Acid Ammonium Salt; O-Desisopropyl O-Desphenyl Sofosbuvir Ammonium Salt
参考CAS号:
Free acid: 1233335-78-8
分子式:
C₁₃H₁₉FN₃O₉P xNH ₃
外观:
白色至Pale Beige Solid
熔点:
>129°C (dec.)
分子量:
411.28
储存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Very Slightly, Heated)
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
PSI 352707 Ammonium Salt is a metabolite of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.