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产品基本信息
产品编号：V094355
产品名称：D-Valinol
产品CAS：09/09/4276
规格含量：5g
产品价格：面议
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产品详细介绍
标准品编号:
V094355
名称:
D-Valinol
别名:
D-2-Amino-3-methyl-1-butanol; (-)-2-Amino-3-methyl-1-butanol; (-)-Valinol; (2R)-2-Amino-3-methyl-1-butanol; (2R)-2-Amino-3-methylbutan-1-ol; (R)-(-)-2-Amino-3-methyl-1-butanol; (R)-(-)-2-Amino-3-methyl-1-butanol; (R)-2-Amino-3-methyl-1-butanol; (R)-2-Amino-3-methylbutan-2-ol; (R)-2-Amino-3-methylbutanol; (R)-Valinol; [(R)-1-(Hydroxymethyl)-2-methylpropyl]amine
CAS号:
09/09/4276
参考CAS号:
S-isomer: 2026-48-4; Deleted CAS: 1206896-36-7
分子式:
C₅H₁₃NO
外观:
Off-White Low-Melting Solid
熔点:
N/A
分子量:
103.16
储存:
冰箱
溶解度:
DMSO (Slightly), Methanol (Slightly)
类别:
Building Blocks; Chiral Molecules;
应用:
D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer's disease.
参考文献
Radl, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2015, ahead of print); Fukunaga, K., et al.: Bioorg. Med. Chem. Lett., 25, 1086 (2015)
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