Mono-O-ethyl Disalicylimide-d5 can be obtained from Methyl Salicylate (M331025) which is an organic ester that is commonly produced naturally by wintergreens. Plants that produce Methyl Salicylate utilize it as a anti-herbivore defense system. Methyl salicylate is also used in high concentrations as a rubefacient to treat joint and muscular pain. Methyl Slicylate is also used as a flavoring agent and often used to provide fragrance to products.