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产品基本信息
产品编号：P701160
产品名称：Prasugrel Hydroxy Thiolactone
产品CAS：947502-66-1
规格含量：5mg
产品价格：面议
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产品详细介绍
标准品编号:
P701160
名称:
Prasugrel Hydroxy Thiolactone
别名:
5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-7a-hydroxy thieno[3,2-c]pyridin-2(4H)-one;
CAS号:
947502-66-1
分子式:
C₁₈H₁₈FNO₃S
外观:
白色至Yellow Solid
熔点:
>45°C (dec.)
分子量:
347.4
储存:
-20°C Freezer
溶解度:
Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Prasugrel Hydroxy Thiolactone, is the metabolite of Prasugrel (P701150), which is a novel thienopyridine. It is also a potent inhibitor of platelet aggregation in vivo.
参考文献
Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),
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