(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-o_512177-83-2_A179105

产品基本信息

产品编号：A179105

产品名称：(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-o

产品CAS：512177-83-2

规格含量：5mg

产品价格：面议

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产品详细介绍

标准品编号:	A179105
名称:	(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one
别名:	(R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one;
CAS号:	512177-83-2
分子式:	C₁₈H₁₉ClFNO₃
分子量:	351.8
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one, is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM.
参考:	Zweemer AJ, et al.: Mol Pharmacol. 2013 Oct;84(4):551-61.;

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