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Fluorobexarotene
产品基本信息
产品编号:F597938
产品名称:Fluorobexarotene
产品CAS:1190848-23-7
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产品价格:面议
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产品详细介绍
标准品编号: F597938
名称: Fluorobexarotene
别名: 2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid; 2-Fluoro-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic Acid
CAS号: 1190848-23-7
分子式: C₂₄H₂₇FO₂
分子量: 366.47
种类: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Fluorobexarotene is a retinoid X receptor (RXR) agonist, which facilitates β-amyloid clearance across blood-brain barrier; RXR activation has the potential to mitigate Aβ brain burden by promoting both the metabolic and BBB clearance of Aβ, offering a novel approach to the treatment of Alzheimer’s disease.
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