Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Fluorobexarotene is a retinoid X receptor (RXR) agonist, which facilitates β-amyloid clearance across blood-brain barrier; RXR activation has the potential to mitigate Aβ brain burden by promoting both the metabolic and BBB clearance of Aβ, offering a novel approach to the treatment of Alzheimer’s disease.