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N-(4-piperazinyl)-oxide ABT 199
产品基本信息
产品编号:N888600
产品名称:N-(4-piperazinyl)-oxide ABT 199
产品CAS:
规格含量:10mg
产品价格:面议
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产品详细介绍
标准品编号: N888600
名称: N-(4-piperazinyl)-oxide ABT 199
别名: 4-(3-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenyl)-1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 1-Oxide; Venetoclax Metabolite M6
分子式: C₄₅H₅₀ClN₇O₈S
外观: Yellow to Dark Yellow Solid
熔点: >170°C (dec.)
分子量: 884.44
储存: -20°C Freezer
溶解度: DMSO (Slightly)
类别: Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: N-(4-piperazinyl)-oxide ABT 199 can be obtained from ABT 199 (A112430) which is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.
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