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Regorafenib N-β-D-Glucuronide O-Tetraacetate
产品基本信息
产品编号:R143330
产品名称:Regorafenib N-β-D-Glucuronide O-Tetraacetate
产品CAS:
规格含量:1mg
产品价格:面议
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产品详细介绍
标准品编号: R143330
名称: Regorafenib N-β-D-Glucuronide O-Tetraacetate
别名: (2R,3R,4S,5S,6S)-2-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
分子式: C₃₄H₃₁ClF₄N₄O₁₂
外观: Light Brown Solid
分子量: 799.08
类别: Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
应用: Regorafenib N-β-D-Glucuronide O-Tetraacetate is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt (R143320), which is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
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