产品基本信息
产品编号：T774146
产品名称：7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel
产品CAS：114915-17-2
规格含量：2.5mg
产品价格：面议
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产品详细介绍
标准品编号:
T774146
名称:
7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel
别名:
7-(2,2,2-Trichloroethyloxycarbonyl)taxol; 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete Benzenepropanoic Acid deriv.; [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-hydroxy-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester Benzenepropanoic Acid; (αR,βS)-β-(Benzoylamino)-α-hydroxy-(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester Benzenepropanoic Acid
CAS号:
114915-17-2
分子式:
C₅₀H₅₂Cl₃NO₁₆
分子量:
1029.3
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel can be used as reactant/reagent for semisynthesis of taxol and Docetaxel via direct esterification of deacetylbaccatin with C13 side chain. It can also be used as reactant/reagent in synthetic preparation and reaction of anti-tumor agents.
参考文献
Colin, M., et al.: Eur. Pat. Appl., EPÂ253739 A1 19870717 (1987); Zhan, H., et al.: Faming Zhuanli Shenqing Gongkai Shuomingshu, CNÂ101020673 A 20070116 (2007);
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