(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide; (2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide; Tyrphostin AG 494
CAS号:
133550-35-3
分子式:
C₁₆H₁₂N₂O₃
分子量:
280.28
类别:
Standards; Enzyme Activators and Inhibitors;
应用:
AG 494 is a potent inhibitor of epidermal growth factor receptor (EGF-R). AG 494 has been found to inhibit cell growth even past the restriction point when receptor activation is no longer necessary; in particular AG 494 causes cells to arrest at late G1 and and during S phase.
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