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产品基本信息
产品编号：A633385
产品名称：3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
产品CAS：2072867-07-1
规格含量：50mg
产品价格：面议
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产品详细介绍
标准品编号:
A633385
名称:
3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
别名:
(R)-3-Amino-N-((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)butanamide
CAS号:
2072867-07-1
分子式:
C₂₆H₂₃F₉N₆O₂
外观:
白色至白色固体
熔点:
>73°C (dec.)
分子量:
622.49
储存:
冰箱保存
溶解度:
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
类别:
Standards; Chiral Molecules;
应用:
3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
文献
Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)
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