Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Labelled analogue of PF 670462, a potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor. PF 670462 has been shown to inhibit PER protein nuclear translocation causing phase shifts in circadian rhythms. PF 670462 attenuates methamphetamine-stimulated locomotion in vivo.
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