Lamivudine (R)-S-Oxide; 4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; [2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; 1,3-Oxathiolane, 2(1H)-pyrimidinone Deriv.; [2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; GI 138870X; Lamivudine EP Impurity H
杂质:
Lamivudine EP Impurity H
CAS号:
160552-54-5
参考CAS号:
(3S)-isomer: 160552-55-6
分子式:
C₈H₁₁N₃O₄S
外观:
白色固体
熔点:
>230°C (dec.)
分子量:
245.26
储存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Water (Slightly, heated)
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
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