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产品基本信息
产品编号：N381200
产品名称：NB-851
产品CAS：943925-09-5
规格含量：25mg
产品价格：面议
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产品详细介绍
标准品编号:
N381200
名称:
NB-851
别名:
(4S)-4-[(1R)1-Hydroxy-2-[[1-[3-(1-methylethyl)phenyl]cyclopropyl]amino]ethyl]-19-methyl-11,16-dioxa-3,18-diazatricyclo[15.3.1.16,10]docosa-1(21),6,8,10(22),17,19-hexaen-2-one; (4S)-4-[(1R)-1-Hydroxy-2-[[1-(3-isopropylphenyl)cyclopropyl]amino]ethyl]-19-methyl-11,16-dioxa-3,18-diazatricyclo[15.3.1.16,10]docosa-1(21),6,8,10(22),17,19-hexaen-2-one;
CAS号:
943925-09-5
分子式:
C₃₃H₄₁N₃O₄
分子量:
543.7
种类:
Research Tools;
应用:
NB-851 is a macrocyclic BACE-1 inhibitor reducing Aβ in brain after administration. Potential treatment for the prevention or maintenance of Alzheimer’s disease.
参考文献
Lerchner, A. et al.: Bioorg. Med. Chem. Lett., 20, 603 (2010);
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