1-Amino-3-nitroadamantane has potential application in co-catalyst for transition metal reactions and maybe a useful intermediate for the synthesis ofÂVildagliptin (V305000), anÂantidiabetic drug that inhibits dipeptidyl peptidase 4 (DPP-4). Vildagliptin exhibits antioxidant properties and may be an apoptotic compound against pancreatic cancer cells.