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产品编号：C380080
产品名称：N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine
产品CAS：444731-74-2
规格含量：10g
产品价格：面议
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产品详细介绍
标准品编号:
C380080
名称:
N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine
别名:
6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole; N-(2-Chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine
CAS号:
444731-74-2
分子式:
C₁₃H₁₂ClN₅
外观:
Pale Orange to Light Brown Solid
熔点:
>216ºC (dec.)
分子量:
273.72
储存:
Hygroscopic, 冰箱保存, under inert atmosphere
溶解度:
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
稳定性:
Hygroscopic
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine is an impurity of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
参考文献
Li, Y., et al.: J. Pharma. Biomed. Anal., 52, 493 (2010); Harris, P.A., et al.: J. Med. Chem., 51, 4632 (2008); Liu, D.Q., et al.: Character. Impurities. Degrad. Mass. Spec., 251 (2011);
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