(3β,16α)-16,17-Epoxy-3-hydroxy-pregn-5-en-20-one Cyclic 1,2-Ethanediyl Acetal is an intermediate used in the synthesis of (16β)-21-(Acetyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione (A187753), which is a useful intermediate that is used in the synthetic preparation of methylhydroxypregnendione via epoxidation, Grignard addition., and oxidation.