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产品基本信息
产品编号：F595670
产品名称：(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
产品CAS：93957-50-7
规格含量：2g
产品价格：面议
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产品详细介绍
标准品编号:
F595670
名称:
(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
别名:
(E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal; (2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal; (E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein
CAS号:
93957-50-7
分子式:
C₂₀H₁₈FNO
外观:
Yellow Solid
熔点:
>132°C (dec.)
分子量:
307.36
储存:
冰箱保存, under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
种类:
Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde is an intermediate in the synthesis of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
参考文献
Sacharia, J.R., et. al.: J. Org. Chem., 75, 7514 (2010); Kim, A., Kim, I.S.: Bull. Korean Chem. Soc., 32, 3748 (2011); Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)
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