8-Chloro-6,11-dihydro-11-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity B; Desloratadine EP Impurity B
杂质:
Desloratadine EP Impurity B
CAS号:
183198-49-4
分子式:
C₁₉H₁₉ClN₂
外观:
白色至Red Solid
熔点:
>65°C (dec.)
分子量:
310.82
储存:
Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
稳定性:
Hygroscopic
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Iso Desloratadine (Desloratadine EP Impurity B) is an impurity of Desloratadine (D290250), which is a nonsedating-type histamine H1-receptor antagonist. Desloratadine is an active metabolite of Loratadine (L469575). Also inhibits generation and release of inflammatory mediators from basophils and mast cells. An impurity arising in the synthesis of Rupatadine (R701650).
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