(βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic Acid Hemicalcium Salt; (βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-benzenepropanoic Acid Calcium Salt (2:1)
CAS号:
1291087-14-3
备用CAS:
Free Acid: 865231-46-5
分子式:
C₅₂H₄₀CaF₆O₆
分子量:
914.94
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
AMG 837 Hemicalcium Salt is used in the synthetic preparation of a novel GPR40 receptor agonist, AMG 837 (A614410). GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity.