rel-2-Amino-1,9-dihydro-9-[(1R,4S)-4-[(phosphonooxy)methyl]-2-cyclopenten-1-yl]-6H-purin-6-one; cis-(±)-2-Amino-1,9-dihydro-9-[4-[(phosphonooxy)methyl]-2-cyclopenten-1-yl]-6H-purin-6-one; Carbovir 5’-Phosphate; Abacavir - In House Impurity; Abacavir Impurities
杂质:
Abacavir - In House Impurity
CAS号:
144490-73-3
分子式:
C₁₁H₁₄N₅O₅P
外观:
白色固体
熔点:
>193°C (dec.)
分子量:
327.23
储存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly, Heated), Methanol (Slightly)
类别:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Carbovir Monophosphate (Abacavir - In House Impurity) is a phosphorylated metabolite of the human immunodeficiency virus inhibitor Carbovir (C177740). It is converted from Abacavir 5’-phosphate by the enzyme N6-Methyl-AMP aminohydrolase (1,2,3).
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