Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
应用:
MRE-269 β-D-Glucuronide can be obtained from 4-Amino-1-butanol (A602120) which is used in the synthesis of NSAIDs with anti-inflammatory properties.4-Amino-1-butanol (A602120) is also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells. MRE-269 β-D-Glucuronide is Glucuronide metabolite of Selexipag (S253150). The drug is first hydrolyzed to an active metabolite, ACT 33679 (CAS#475085-57-5, planned) in the liver and then glucuronidated afterwards.
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