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产品基本信息
产品编号：B287550
产品名称：Benzo[a]pyrene Diol Epoxide
产品CAS：58917-67-2
规格含量：25mg
产品价格：面议
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产品详细介绍
标准品编号:
B287550
名称:
Benzo[a]pyrene Diol Epoxide
别名:
(7R,8S,8aS,9aR)-rel-7,8,8a,9a-Tetrahydrobenzo[10,11]chryseno[3,4-b]oxirene-7,8-diol; (7α,8β,8aα,9aα)-7,8,8a,9a-Tetrahydrobenzo[10,11]chryseno[3,4-b]oxirene-7,8-diol; (±)-7α,8β-Dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene; (±)-7β,8α-Dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene; (±)-anti-BPDE; anti-Benzo[a]pyrene-7,8-diol-9,10-epoxide; trans-7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene;
CAS号:
58917-67-2
分子式:
C₂₀H₁₄O₃
外观：
Pale Yellow to Yellow Solid
熔点:
164-166°C
分子量:
302.32
储存:
Amber Vial, 冰箱保存, Under Inert Atmosphere
溶解度:
DMSO (Slightly)
稳定性:
Light Sensitive
类别:
Standards; Environmental Standards, Mutagens and Metabolites;
应用:
Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway. Benzo [a]pyrene diol epoxide (BPDE), a carcinogen present in tobacco smoke as well as in environmental pollution, induces esophageal carcinogenesis.
文献
Cavalieri, E., et al.: Biochem. Pharmacol., 1988, 37, 2173 (1988); Conney, A., et al.: Cancer Res., 42, 4875 (1982); Penning, T., et al.: Chem. Res. Toxicol., 9, 84 (1996); Lu, D., et al.: Chem. Res. Toxicol., 2011, 24, 1905 (2011);
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