Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly, Sonicated)
类别:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
4BP-TQS is an agonist of human α7 nicotinic acetylcholine receptor (a7-nAChR), activates the channel via binding to an allosteric transmembrane site. Maximal activation of a7-nAChR by 4BP-TQS is eight fold greater than activation by a maximum dose of acetylcholine (Ach), and 4BP-TQS can poteniate an EC10 concentration of ACh to invoke a response that is 540-fold higher than the maximal dose of ACh alone.
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