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产品基本信息
产品编号：T294460
产品名称：(6R)-5,6,7,8-Tetrahydro-6-(propylamino)-1-naphthalenol
产品CAS：101470-24-0
规格含量：10mg
产品价格：面议
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产品详细介绍
标准品编号:
T294460
名称:
(6R)-5,6,7,8-Tetrahydro-6-(propylamino)-1-naphthalenol
别名:
(R)-5,6,7,8-tetrahydro-6-(propylamino)-1-naphthalenol
CAS号:
101470-24-0
参考CAS号:
Racemic: 78950-82-0
分子式:
C₁₃H₁₉NO
外观:
Very Dark Brown to Black Solid
分子量:
205.3
溶解度:
Chloroform (Slightly), Methanol (Slightly)
类别:
Building Blocks; Miscellaneous;
应用:
(6R)-5,6,7,8-Tetrahydro-6-(propylamino)-1-naphthalenol is an intermediate in the production of antipsychotic agents and antiparkinson medications, such as ent-Rotigotine (R700705), which is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
参考文献
Homan, E., et al.: Bioorg. Med. Chem., 7, 1263 (1999); Biswas, S., et al.: J. Med. Chem., 51, 101 (2008); Loschmann, P., et al.: Eur. J. Pharmacol., 166, 373 (1989); Edgar, D., et al.: J. Pharmacol. Exp. Ther., 283, 757 (1997); Ferreira, J., et al.: Lancet, 355, 1333 (2000); Arnulf, I., et al.: Neurology, 58, 1019 (2002); Wisor, J., et al.: Neuroscience, 132, 1027 (2005)
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