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产品基本信息
产品编号：A602985
产品名称：4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
产品CAS：956025-99-3
规格含量：100mg
产品价格：面议
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产品详细介绍
标准品编号:
A602985
名称:
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
别名:
3-[(3-Bromophenyl)methyl]-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-BrB-PP1;
CAS号:
956025-99-3
分子式:
C₁₆H₁₈BrN₅
状态：
灰白色至浅褐色固体
熔点：
140-142°C
分子量:
360.25
储存：
冰箱保存
溶解性:
Chloroform (Slightly), Methanol (Slightly)
类别:
Standards; Enzyme Activators and Inhibitors;
应用:
4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine is a small molecule Akt inhibitor. The kinase Akt is a key signaling node in regulating cellular growth and survival.
参考:
Eblen, S., et al.: J. Biol. Chem., 278, 14926 (2003), Lindsley, C., et al.: Bioorg. Med. Chem. Lett., 15, 761 (2005), Manning, B., et al.: Cell, 129, 1261 (2007), Heerding, D., et al.: J. Med. Chem., 51, 5663 (2008),
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